I am not convinced that the fresh new title faithfully shows the brand new contents of brand new papers

Authors’ effect

What is the method for determining fast-growing and slow-growing proteins-coding genes? In case the method is simply “Play with Ka”, I’d argue that individuals have complete that just before.

Authors’ response

I’ve altered the newest name to help you “Nonsynonymous replacing rate (Ka) are a comparatively uniform parameter having defining fast-growing and you can slow-developing necessary protein-programming genes”. I have looked the newest related literature carefully and now have maybe not discovered guides that have over such as for example comprehensive critiques on the strategies.

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Demuth JP, De Bie T, Stajich JE, Cristianini N, Hahn MW: Brand new progression away from mammalian gene group. PLoS You to definitely. 2006, 1: e85-/journal.pone.0000085.

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